Höfundar: Juan Ouyang

Abnormalities of the neuro-gliogenic switch in Mendelian disorders of the epigenetic machinery

Loss of epigenetic machinery components causes neuronal DNA methylation abnormalities

A systematic CRISPR-screen targeting EM-genes to uncover shared transcriptional dysregulations during neurodevelopment

A strategy to identify functionally relevant DNA methylation abnormalities in neurons

Differentiation rate affects DNA methylation abnormalities in neurons with epigenetic machinery knockout

Abnormalities of the neuro-gliogenic switch in Mendelian disorders of the epigenetic machinery

A systematic CRISPR-screen targeting EM-genes to uncover shared transcriptional dysregulations during neurodevelopment

A strategy to identify functionally relevant DNA methylation abnormalities in neurons

Elucidating functionally important CpG sites in Neurodevelopmental Disorders via systematic knockout of EM genes

Systematic disruption of EM genes to understand transcriptional effect and role in neurodevelopmental disorders.

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