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PRESENTED IN ENGLISH

Biomedical and Health Sciences Conference at the University of Iceland

Pharmaceutical Sciences I

Presenters:

Time, type of presentation:

Session Chair: Elvar Örn Viktorsson

12:30-12:45: Dual-Activity Compounds for Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor
12:45-13:00: Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug Formulations
13:00-13:15: The Effect of Trehalose, Antioxidants, and Acetate Buffer Concentration on Oxytocin Stability
13:15-13:30: Chitotriazolan (Chito-1,2,3-triazole) Derivatives; Synthesis, Characterization and Evaluation of Antibacterial Activity

Abstracts in session A-Z

Chitotriazolan (Chito-1,2,3-triazole) Derivatives; Synthesis, Characterization and Evaluation of Antibacterial Activity

Sankar Rathinam, In the present work, design and synthesis of chitotriazolan via „Click reaction“ copper catalyzed azide alkyne cycloaddition reaction. Chitotriazolan’s derivatives characterized by FT-IR, 1H, and 2D NMR. Finally investigated antibacterial activity.

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Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug Formulations

Main Author: Manisha Prajapati
Short description of the abstract: The study aimed to examine the cytotoxicity of two different CDs; HPβCD and RMβCD in mouse retinal explants and their localization within the retinal tissues.

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Dual-Activity Compounds for Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor

Sebastian Oddsson
The abstract describes a successful first step in the drug discovery process for potential new Alzheimer’s drugs. That is the identification of two drug leads in a virtual screening with a new activity profile.

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The Effect of Trehalose, Antioxidants, and Acetate Buffer Concentration on Oxytocin Stability

Main author: Mostafa Ghasemisarabbadieh
Short description: The stability effect of oxytocin formulations with different buffer concentrations, select antioxidants and trehalose were studied. Lower acetate buffer concentrations improved oxytocin’s stability but the other additives did not help.

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