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PRESENTED IN ENGLISH

Biomedical and Health Sciences Conference at the University of Iceland

Pharmaceutical analysis

Presenters:

Time, type of presentation:

Session Chair: Elvar Örn Viktorsson

14:20-14:35: The effect of 18-crown-6 on oxytocin stability in aqueous buffer solutions
14:35-14:50: Chiral separation and spatial distribution of usnic acid enantiomers in lichens
14:50-15:05: Did we have enough evidence to describe galantamine as an allosteric modulator of nicotinic receptors?
15:05-15:20: Development of production process for N,N,N-trimethylchitosan

Abstracts in session A-Z

Chiral separation and spatial distribution of usnic acid enantiomers in lichens

Main author: Maonian Xu.
Short description of the abstract: A chiral UHPLC method was developed and validated to determine usnic acid enantiomer contents in lichens, and the compounds were visualized from thallus cross sections using mass spectrometry imaging and fluorescence microscopy.

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Development of production process for N,N,N-trimethylchitosan

Main author: Vivien Nagy
A new production process for the synthesis of N,N,N-trimethylchitosan was developed and optimized with the Design of Experiment approach to obtain a highly trimethylated, water soluble chitosan derivative with significant antimicrobial activity.

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Did we have enough evidence to describe galantamine as an allosteric modulator of nicotinic receptors?

Natalia M Kowal Galantamine is not a positive modulator of nicotinic receptors.

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The effect of 18-crown-6 on oxytocin stability in aqueous buffer solutions

Main author: Benjamin R. Sveinbjörnsson
Short description: In a mechanistically guided approach, the effects of 18-crown-6 on the stability of oxytocin in solution was studied. 18-crown-6 interacted with oxytocin and stabilized it in citrate/phosphate buffer but destabilized it in acetate buffer.

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