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ÖRFYRIRLESTUR

Líf - og heilbrigðisvísindaráðstefna Háskóla Íslands 2021

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UPPTAKA AF ÖRFYRILESTRUM

Cyanide as a public health issue: Mechanistic approach with water soluble α-amino-acid complexes of molybdenum

Main author: Thiago Valdares de Oliveira. Study of the catalyst throughout the catalytic cycle is expected to elucidate important information that will aid in development of a successful formulation for a catalytic detoxification for cyanide poisoning.

LESA ÁGRIP

Effect of acidic counterion on the increase of aqueous solubility of dovitinib

Suppakan Sripetch. Increase aqueous solubility of the poorly water-soluble drug, dovitinib, by ion-pairing

LESA ÁGRIP

Enantiomer Selectivity and Efficacy in Cyanide Poisoning Antidote

Main author: Alicja Weronika Kahlan.
This work presents a new, potential antidote for cyanide poisoning which both, in vivo and ex vivo, showed low cytotoxicity and high efficiency. Discussed molybdenum complex is capable of converting cyanides into thiocyanates acting as sulfur donor and catalyst.

LESA ÁGRIP

Interaction of Cytochrome c Oxidase with Molybdenum Complexes and Cyanide

Main author: Norbert Bedő
The abstract is a short summary of a project, that focuses on a particular enzyme (CcO), including its inhibition with cyanide and a possible reactivation of the activity using different molybdenum sulfur complexes as candidates for the enzymatic reactivation.

LESA ÁGRIP

Isolation and quantification of extracellular vesicles (EVs) from breast epithelial cell lines

Berglind Eva Benediktsdóttir. This mini-presentation will show the evolvement of the isolation and characterization protocol for extracellular vesicles (EVs) from breast epithelial cell lines that is now sufficient to move forward to the next steps in creating an EV nanodrug delivery system targeting breast cancer subtypes.

LESA ÁGRIP

New function of ATG7

Kevin Ostacolo, Margrét Helga Ögmundsdóttir

LESA ÁGRIP

The adjuvants mmCT and dmLT enhance antibody response to Pn1-CRM in a neonatal murine model

Jenny Lorena Molina Estupiñan. Subcutaneous and intranasal immunization of the adjuvants dmLT and mmCT enhanced the antibody response to the pneumococcal conjugate vaccine Pn1-CRM in a neonatal murine model.

LESA ÁGRIP

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