Main author: Maonian Xu.
Short description of the abstract: A chiral UHPLC method was developed and validated to determine usnic acid enantiomer contents in lichens, and the compounds were visualized from thallus cross sections using mass spectrometry imaging and fluorescence microscopy.
Main author: Maonian Xu.
Main Author: Manisha Prajapati
Short description of the abstract: The study aimed to examine the cytotoxicity of two different CDs; HPβCD and RMβCD in mouse retinal explants and their localization within the retinal tissues.
Main author: Vivien Nagy
A new production process for the synthesis of N,N,N-trimethylchitosan was developed and optimized with the Design of Experiment approach to obtain a highly trimethylated, water soluble chitosan derivative with significant antimicrobial activity.
Main author: Norbert Bedő
The abstract is a short summary of a project, that focuses on a particular enzyme (CcO), including its inhibition with cyanide and a possible reactivation of the activity using different molybdenum sulfur complexes as candidates for the enzymatic reactivation.
Arsalan Amirfallah: We analyzed if miR-21-3p expression can predict patient prognosis. Our results indicate that high miR-21-3p expression is associated with a worse prognosis for breast cancer patients and it affects pathways that support breast tumor proliferation.
Seyedeh Parinaz Mahdavi
This study aimed to determine the expression level of mir-99b-5p in TNBC tissues and study the mir-related cellular parameters. Consequently, the effect of miR-99b-5p on BC cells especially MDA-MB-231 was shown the tumor-suppressor function.
GFPT2 is upregulated in breast epithelial–mesenchymal transition and involved in oxidative stress regulation
Main author: Qiong Wang. To study metabolic reprogramming in different Epithelial–mesenchymal transition states, we analyzed proteomic changes following EMT in breast gland. We found out enzyme GFPT2 is involved in oxidative stress regulation and a potential target for breast cancer therapy.
Aðalhöfundur: Arna Steinunn Jónasdóttir
Peroxidasin (PXDN) is a secreted enzyme that has been linked with EMT, fibrosis and cancer progression in ovarian cancer and melanoma. Here we look into if PXDN may play a role on breast cancer progression.
Main author: Kimberley Anderson. Here, we present a novel mouse model for the neurodevelopmental disorder, Pilarowski-Björnsson syndrome (PBS). We have observed striking sexually dimorphic phenotypes in these mice, and will use our findings to improve mechanistic understanding of the disorder.
Dietary fish oil induces recruitment of differentiated NK cells and enhances resolution of antigen-induced peritonitis
Main author: Kirstine Nolling Jensen
In this study we further characterized the effects of fish oil on NK cells and resolution of inflammation and saw increased recruitment of differentiated NK cells, possibly through CCL5 and CXCL12, and increased soluble TNFRII, possibly neutralizing TNF.